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The red face: Dermatomyositis

Identifieur interne : 002D19 ( Main/Exploration ); précédent : 002D18; suivant : 002D20

The red face: Dermatomyositis

Auteurs : Marcus R. Stonecipher [États-Unis] ; Jeffrey P. Callen [États-Unis] ; Joseph L. Jorizzo [États-Unis]

Source :

RBID : ISTEX:84B53C16D0070E489D370448AC96D02D744907BB

English descriptors

Abstract

Abstract: Dermatomyositis (DM) is a disease that manifests as an inflammatory myopathy typically producing a symmetric proximal muscle weakness and a characteristic cutaneous eruption.1–3 This disorder is closely related to polymyositis (PM), which has all the clinical features of DM without the presence of skin disease. Both of these disorders are of unknown etiology, but pathogenetic mechanisms are believed to involve immunologically mediated muscle damage.4 Both DM and PM may occur in the presence of other collagen vascular diseases such as lupus erythematosus, scleroderma, Sjögren's syndrome, rheumatoid arthritis, and various vasculitides. Dermatomyositis seems to be characterized by an increased frequency of internal malignancy, whereas malignancy association in patients with PM is less clearly established. Recent data suggest that PM, as well as DM, occurs in children. Both DM and PM are associated with morbidity and mortality and, therefore, prompt and aggressive therapy is necessary. In this review we emphasize practical clinical aspects of DM.

Url:
DOI: 10.1016/0738-081X(93)90062-H


Affiliations:


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Le document en format XML

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<term>Abnormality</term>
<term>Acad dermatol</term>
<term>Acta neurol</term>
<term>Adult patients</term>
<term>Antinuclear antibody</term>
<term>Arch dermatol</term>
<term>Arch intern</term>
<term>Arthritis</term>
<term>Arthritis rheum</term>
<term>Autoantibody</term>
<term>Biopsy</term>
<term>Bohan</term>
<term>Bony prominences</term>
<term>Calcinosis</term>
<term>Callen</term>
<term>Cardiac</term>
<term>Cardiac disease</term>
<term>Chest radiographs</term>
<term>Childhood dermatomyositis</term>
<term>Clin</term>
<term>Clinic</term>
<term>Clinical features</term>
<term>Clinical manifestations</term>
<term>Complete history</term>
<term>Conduction defects</term>
<term>Congestive heart failure</term>
<term>Connective tissue disease</term>
<term>Corticosteroid</term>
<term>Corticosteroid dosage</term>
<term>Corticosteroid therapy</term>
<term>Creatine</term>
<term>Creatine kinase</term>
<term>Current time</term>
<term>Cutaneous</term>
<term>Cutaneous disease</term>
<term>Cutaneous lesions</term>
<term>Dermatol</term>
<term>Dermatology</term>
<term>Dermatology callen</term>
<term>Dermatomyositis</term>
<term>Dermatomyositis rheum</term>
<term>Disease process</term>
<term>Dysphagia</term>
<term>Eruption</term>
<term>Erythematosus</term>
<term>Esophageal involvement</term>
<term>Greater risk</term>
<term>Heliotrope eruption</term>
<term>Immunosuppressive</term>
<term>Immunosuppressive agent</term>
<term>Immunosuppressive agents</term>
<term>Immunosuppressive therapy</term>
<term>Inflammatory</term>
<term>Inflammatory myopathy</term>
<term>Inflammatory myositis</term>
<term>Intern</term>
<term>Internal malignancy</term>
<term>Interstitial lung disease</term>
<term>Intramuscular injections</term>
<term>Jorizzo</term>
<term>Jorizzo clinics</term>
<term>Juvenile dermatomyositis</term>
<term>Laboratory abnormalities</term>
<term>Lesion</term>
<term>Liver biopsy</term>
<term>Lower frequency</term>
<term>Lung disease</term>
<term>Lupus</term>
<term>Lupus erythematosus</term>
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<term>Malignant</term>
<term>Malignant disease</term>
<term>Malignant lesions</term>
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<term>Methotrexate</term>
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<term>Multiple side effects</term>
<term>Muscle biopsy</term>
<term>Muscle damage</term>
<term>Muscle disease</term>
<term>Muscle enzymes</term>
<term>Muscle weakness</term>
<term>Myopathy</term>
<term>Myositis</term>
<term>Nailfold capillary microscopy</term>
<term>Nailfold changes</term>
<term>Nuclear protein</term>
<term>Overlap category</term>
<term>Overlap syndromes</term>
<term>Papular lesions</term>
<term>Pathogenetic mechanisms</term>
<term>Periungual telangiectasias</term>
<term>Physical examination</term>
<term>Plasma exchange</term>
<term>Poikiloderma</term>
<term>Poikilodermatous eruption</term>
<term>Polymyositis</term>
<term>Poor prognosis</term>
<term>Poor prognostic sign</term>
<term>Poorer prognosis</term>
<term>Prognosis</term>
<term>Prognostic factors</term>
<term>Pulmonary disease</term>
<term>Pulmonary fibrosis</term>
<term>Pulmonary function testing</term>
<term>Pulmonary involvement</term>
<term>Reichlin</term>
<term>Rheum</term>
<term>Rheumatoid arthritis</term>
<term>Semin arthritis rheum</term>
<term>Serum levels</term>
<term>Serum multiphasic analysis</term>
<term>Several authors</term>
<term>Several studies</term>
<term>Skin change</term>
<term>Skin disease</term>
<term>Skin lesions</term>
<term>Stonecipher</term>
<term>Striated muscle</term>
<term>Syndrome</term>
<term>Systemic corticosteroids</term>
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<term>Tissue diseases</term>
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<div type="abstract" xml:lang="en">Abstract: Dermatomyositis (DM) is a disease that manifests as an inflammatory myopathy typically producing a symmetric proximal muscle weakness and a characteristic cutaneous eruption.1–3 This disorder is closely related to polymyositis (PM), which has all the clinical features of DM without the presence of skin disease. Both of these disorders are of unknown etiology, but pathogenetic mechanisms are believed to involve immunologically mediated muscle damage.4 Both DM and PM may occur in the presence of other collagen vascular diseases such as lupus erythematosus, scleroderma, Sjögren's syndrome, rheumatoid arthritis, and various vasculitides. Dermatomyositis seems to be characterized by an increased frequency of internal malignancy, whereas malignancy association in patients with PM is less clearly established. Recent data suggest that PM, as well as DM, occurs in children. Both DM and PM are associated with morbidity and mortality and, therefore, prompt and aggressive therapy is necessary. In this review we emphasize practical clinical aspects of DM.</div>
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